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How to Lower Blood Pressure While on Testosterone Replacement Therapy

Testosterone replacement therapy is an excellent treatment option for men suffering from low testosterone levels; however, its long-term use is known to thicken blood and decrease HDL cholesterol, potentially increasing blood pressure (1).

If you suffer from high blood pressure, it’s essential that you manage its symptoms by taking medications and engaging in healthy habits.


Blood pressure can be a silent killer; most people don’t realize they have it until one of its serious complications like stroke, heart attack or renal disease strike. Therefore, it is crucial that regular measurements be taken with a sphygmomanometer at home in a relaxed position (sitting or standing up straight without lying down, arm rested at side with elbow bent slightly against table and restrained by arm at sides and checked both morning and evening for optimal health.

Low testosterone can result in low systolic and diastolic pressure levels, having an adverse impact on arterial health. Studies have also revealed that men with lower testosterone have an increased risk of obesity and diabetes – both conditions known to elevate blood pressure – because lower testosterone levels translate to reduced lean body mass and muscle strength, leading to less HDL cholesterol to protect arteries from plaque build-up.

Testosterone replacement therapy can help lower body fat while increasing muscle mass. This may also improve both systolic and diastolic blood pressure. However, you shouldn’t rely solely on testosterone replacement therapy to lower your blood pressure without making other lifestyle changes as well.

Studies published in Hypertension demonstrated that adding testosterone treatment to supervised exercise programs did not enhance their effects on artery health. This 2-x-2 factorial randomised trial involved patients randomly assigned either daily transdermal AndroForte5 (testosterone 2% gel) or placebo along with an intensive 20-week exercise training program. Primary efficacy outcomes included total serum testosterone at weeks 12 and 20; secondary outcomes included changes in IIEF and AMS questionnaire scores as well as responses to GAQ at these visits.

While this study didn’t demonstrate significant benefits from exercise and testosterone combined, it did highlight the significance of maintaining regular physical exercise as well as regularly monitoring your blood pressure with an automatic home sphygmomanometer to make this process simpler and more convenient.


An effective diet is key for maintaining optimal levels of testosterone. Avoid refined sugars and salt as well as processed food and animal products. Instead, choose a diet enriched in whole foods and low glycemic index foods which will help regulate weight and blood pressure.

Maintaining adequate hydration levels in your body is also key for health benefits, including protecting yourself against high blood pressure and other serious medical conditions. A dehydrated body increases risk for high blood pressure as well as other ailments.

Testosterone is an essential hormone in our bodies, playing various important roles such as increasing libido, energy levels and metabolism while changing body composition (muscle mass to fat ratio). Furthermore, testosterone has also been known to strengthen bone density, reduce inflammation and decrease “bad” LDL cholesterol.

Testosterone also raises levels of nitric oxide in your body, relaxing arteries and decreasing resistance to blood flow – this helps lower your blood pressure over time while protecting against cardiovascular disease and diabetes. Testosterone can even improve HDL cholesterol levels which is an added bonus!

However, long-term TRT may have detrimental effects on cardiovascular system if used at high doses, in combination with other male sex hormones or misused. Some of these side effects include heart attack, mini strokes, liver disease and seizures as well as sudden mood shifts, aggressive or unfriendly behavior, hallucinations or mental health changes.

Also, testosterone can increase the risk of prostate cancer, reduced sperm count and blood clots in the lungs or legs – risks which are increased among older men. A study conducted comparing TRT risks vs placebo for men aged over 65 demonstrated that benefits far outweighed risks.

Testosterone replacement therapy can be a highly effective means of treating low testosterone in men, but it’s crucial that all possible efforts be made to mitigate risk. Regular follow up appointments with your physician as well as using at-home monitoring devices may ensure you stay on track. A high blood pressure reading could indicate a bigger health concern so take it seriously!

Stress Management

Testosterone is an important hormone for human metabolism, muscle mass, fat levels and bone density. Additionally, testosterone helps relax blood vessel smooth layers to improve flow and lower blood pressure – but high amounts can also increase cholesterol, triglycerides and blood sugar.

An increased risk of heart disease and strokes. An overproduction of cortisol – the stress hormone responsible for high blood pressure. Additionally, high levels of cortisol can disrupt other key hormones including estrogen and progesterone that are essential in maintaining balance in body processes – leading to weight gain, decreased libido, and changes in mood.

If you have had cardiovascular issues in the past, or high blood pressure is a risk factor, or are considering testosterone replacement therapy (TRT), consult with your physician prior to initiating it. According to recent research findings, however, TRT does not directly cause heart disease or worsen existing heart conditions in most men – lifestyle factors and age are more likely to be responsible.

Researchers conducted the study by dividing 536 male and 666 female Black subjects into hypertensive and normotensive groups. Blood samples from each participant were also taken and used to measure hematocrit levels, cholesterol, blood sugar levels and blood pressure. Researchers noted that those who had low testosterone levels experienced higher triglyceride and systolic blood pressure readings, lower HDL cholesterol levels and greater total cholesterol counts than their counterparts with higher testosterone levels.

Ideal, accurate blood pressure checks should be carried out at home for best results. Sit comfortably and rest your arms lightly by your sides – an automatic blood pressure cuff can record and monitor results automatically and keep a running average. Before beginning TRT it’s also beneficial to get an initial baseline reading so you know what normal is; especially important if there has been history of cardiovascular problems or heart disease – to set realistic expectations during and post treatment monitoring is vitally important.


The male hormone testosterone stimulates bone marrow to produce red blood cells, providing oxygenated blood to muscles and brain tissue. Unfortunately, however, testosterone may increase risk for thick blood clots that could potentially lead to heart attacks and strokes; so for this reason it’s vital that men follow these recommendations for controlling their blood pressure.

An adequate night’s rest is vital to proper body functioning. A lack of sleep has been linked with numerous health conditions, including high blood pressure. Sleeping for 8+ hours each night could help lower blood pressure levels. A diet low in fat and salt, regular exercise, and stress management techniques may also contribute to lower blood pressure levels.

No one knows exactly how testosterone affects a man’s blood pressure; however, low testosterone has been shown to increase heart disease risk as well as conditions associated with high blood pressure like diabetes and obesity. Furthermore, low testosterone has also been linked to depression and mood swings.

Blood pressure typically changes throughout the day. It tends to drop during times of rest when testosterone production peaks; conversely, during stressful or active moments when production decreases significantly, it tends to spike.

Some high blood pressure medications may cause sexual side effects, particularly older beta blockers like propranolol (Inderal LA or Innopran XL). If your blood pressure medication makes it hard to get an erection, talk to your physician about switching to one less likely to have this side effect.

As part of your healthcare team, it’s also vitally important that you inform both your physician and pharmacist of all medications, vitamins, nutritional supplements, herbal products you are currently taking or considering using, such as aspirin, acetaminophen or any over-the-counter pain relievers and herbal or vitamin supplements you might use or intend taking in the future. Also inform them if any illegal substances have ever been used or abuse history exists so your physician can decide if you require dose adjustments on any of your medications or be closely monitoring you for potential sexual changes or monitoring closely for potential changes.

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